Functional substrate mapping and ablation for post-infarct VT
We have demonstrated that evoked delayed potential mapping and ablation in patients with post-myocardial infarction VT and, in particular, in patients with non-transmural small infarctions after acute reperfusion, is associated with excellent outcome on follow-up.
Multicenter international registry on evoked delayed potential (EDP) ablation
Since 2019, patients with prior myocardial infarction undergoing VT ablation based on EDP elimination at 6 international centers are included in a prospective registry. Our aims are to assess EDP ablation outcome when performed at different centers following a uniform protocol and to identify patients who benefit most from this substrate modification approach.
Mapping and ablation of the functional substrate of post-MI VT with mini-, micro- and conventional electrodes. A multicenter prospective study.
Our objective is to assess the accuracy of simultaneous conventional and micro-electrode mapping using the QDOT catheter for EDP identification in patients with prior myocardial infarction compared to multielectrode mapping with the Pentaray catheter.
Area-weighted UV in patients undergoing post-MI VT ablation
This project focuses on finding an accurate parameter used to quantify viable myocardium in patients with ICM and use it to predict heart failure events. The proposed parameter is easily available from mapping and is validated in a second consecutive cohort.
DCM VT study
The treatment of recurrent ventricular tachycardia in patients with DCM can be challenging. Although catheter ablation is increasingly being performed, real world data on long-term outcome after ablation is only sparsely available. This large international multicenter registry of 9 tertiary centers on 3 continents was initiated by WECAM electrophysiologists. We aim to provide data on outcome of VT ablation to enable optimal patient selection, ablation and follow-up strategies.