Towards the curative treatment of VT in congenital heart disease

Towards the curative treatment of VT in congenital heart disease

project towards the curative treatment of vt in congenital heart disease wecam


Mapping studies

Advances in surgical techniques have improved life expectancy in patients with CHD, exposing more patients to the risk of late ventricular tachycardia and sudden death. The VT substrate can be identified by detailed 3D electroanatomical mapping and RFCA targeting the VT substrate is the most promising therapy to prevent VT.

project mapping studies wecam

In tetralogy of Fallot patients with a slow-conducting anatomical isthmus who undergo pulmonary valve replacement, intraoperative cryoablation of anatomical isthmuses should be performed. Furthermore, confirmation of bidirectional conduction block across the cryoablation line by intraoperative differential pacing may improve the VT-free survival.

Our aim is to non-invasively predict the VT substrate in patients with tetralogy of Fallot and other congenital heart disease. We systematically perform diagnostic tests in the outpatient clinic to screen patients for high-risk criteria. Patients considered high risk or before re-valving are offered an electrophysiological study, providing electroanatomical validation.

Key reviews

Clinical Aspects and Ablation of Ventricular Arrhythmias in Tetralogy of Fallot.
Cardiac electrophysiology clinics
Edition: 1877-9182 | Pages: 285-294

Key publications

Noninvasive Identification of Ventricular Tachycardia-Related Anatomical Isthmuses in Repaired Tetralogy of Fallot: What Is the Role of the 12-Lead Ventricular Tachycardia Electrocardiogram.
Edition: 2405-500X | Pages: 1308-1318
Slow Conducting Electroanatomic Isthmuses: An Important Link Between QRS Duration and Ventricular Tachycardia in Tetralogy of Fallot.
Edition: 2405-500X | Pages: 781-793
Impact of surgery on presence and dimensions of anatomical isthmuses in tetralogy of Fallot.
Edition: 1355-6037 | Pages: 1200-1207
Arrhythmogenic anatomical isthmuses identified by electroanatomical mapping are the substrate for ventricular tachycardia in repaired Tetralogy of Fallot.
Edition: 0195-668X | Pages: 268-276
Re-entry using anatomically determined isthmuses: a curable ventricular tachycardia in repaired congenital heart disease.
Edition: 1941-3149 | Pages: 102-109
Left-sided ablation of ventricular tachycardia in adults with repaired tetralogy of Fallot: a case series.
Edition: 1941-3149 | Pages: 889-897
Catheter ablation of ventricular tachycardia after repair of congenital heart disease: electroanatomic identification of the critical right ventricular isthmus.
Edition: 0009-7322 | Pages: 2241-2252
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